Visualize PD Symptom Response to DBS Settings
Kinesia ProView™ is designed to quickly visualize quantitative motor symptom severity response during DBS programming for Parkinson’s. The system provides a standardized platform to quantitatively assess how symptoms such as tremor, bradykinesia, and dyskinesias change in response to specific DBS settings.
Deep brain stimulation (DBS) involves implanting an electrode in a specific area of the brain, and then adjusting stimulation settings to a level that alleviates symptoms without causing side effects. While DBS has been shown effective for treating Parkinson’s, there can be disparity in outcomes among implanted patients due to varied postoperative management, particularly concerning DBS programming optimization. Variability may be due to programmer training and experience and time required to determine an optimal set of DBS parameters. Programmers can adjust several types of settings including the contact, polarity, frequency, pulse width, and amplitude of stimulation. This creates a tremendous amount of possible combinations that must be evaluated over multiple types of motor symptoms in a limited time frame during an office visit.
The system integrates a secure, HIPAA compliant web application and a broadband enabled tablet interface with wireless patient sensors. During a programming assessment, the patient wears a wireless sensor to assess motor symptoms at each DBS setting. A tablet PC application creates color-coded tuning maps as the programming session progresses, which display specific symptom severities as a function of stimulation settings. This tuning map allows physicians to visually assess the programming parameter space and optimize the final settings for specific symptoms and battery consumption. Once the programming session is complete, patient data and tuning maps are transmitted via broadband connectivity to a cloud-based server for storage, reporting, and trending using the Kinesia web application.